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Gut microbiome alterations affect glioma development and Foxp3 expression in tumor microenvironment in mice

doi: 10.3389/fcell.2025.1602320 Received 29 March 2025 Accepted 15 May 2025 Published 30 June 2025 Volume 13 - 2025 Edited by Tadahiro Nagaoka, Fujita Health University, Japan Reviewed by Kulvinder Kochar Kaur, Kulvinder Kaur Centre For Human Reproduction, India Ashot Avagimyan, Yerevan State Medical University, Armenia Updates Copyright 2025 Chatterjee and Thakur

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Its elimination halflife in mice was reported to be under 30 min [14]

ROS acts as a central hub connecting ferroptosis to PCa pathogenesis, amplified by inflammatory signals and redox-sensitive transcription factors (e.g., Nrf2, HIF-1) that either directly enhance oxidative stress or indirectly modulate ferroptosis susceptibility [Figure 2A]