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47 Chalcones (1,2-diphenyl-2-propen-1-one) belonging to the flavonoid family, such as isoliquiritigenin (licorice roots) and xanthohumol (hops), have been shown to decrease pulmonary inflammation caused by lipopolysaccharide (LPS)

Glucose, amino acids and triglycerides increase in the blood

have discovered that berberine improves cardioprotection by upregulating miR-340-5p and inhibiting high mobility group box 1 (HMGB1)-mediated inflammatory response (Long et al., 2023)

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Firstly, although many drugs show promising results in animal models, there is a lack of sufficient large-scale clinical trial data to support their efficacy and safety across diverse patient populations (206)

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