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Effect of statin on age-related hearing loss via drug repurposing

Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019)

The somatostatinergic system also encompasses cortistatin, an evolutionary-related peptide that shares high structural and functional similarity to somatostatin although derived from a distinct gene (de Lecea et al., Besides the initially described expression site in the hypothalamus, somatostatin is widely distributed in the rodent brain with dense expression in the cortex, amygdala, limbic and sensory system, periaqueductal central gray and paraventricular, ventromedial and arcuate hypothalamic nuclei (Finley et al., 1985

For liver protection and detox, NAC raises glutathione so the liver can knock out toxins better

10.1186/s12891-025-09258-8 12 BagurR.HajnczkyG

9 , e0003504 (2015)