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Ann Oncol 18 : 299304 Rubbia-Brandt L, Lauwers GY, Wang H, Majno PE, Tanabe K, Zhu AX, Brezault C, Soubrane O, Abdalla EK, Vauthey JN, Mentha G, Terris B (2010) Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis

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The former, employing microsomal omega-1 oxidization, oxidized MEK to 3-hydroxy-2-butanone, which was subsequently reduced to 2,3 butanediol

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