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36 Ferric ions are then released from the transferrin complex by endosomal acidification and reduced to ferrous ions (Fe 2+ ) by six-transmembrane epithelial antigen of prostate 3 (STEAP3), Tf will separate from its receptor TfR1 and re-enter the bloodstream to capture ferric ions

Glutathione conjugation protects against AQ-induced toxicity and GSTP1 is able to conjugate its quinoneimine metabolites AQ-QI and DEA-QI with glutathione

Despite our observation that CAR loss-of-function during sepsis leads to the downregulation of various hepatic metabolic genes, including those involved in the metabolism of bile acids and fatty acids, as well as genes from the TCA cycle, additional metabolic data, such as the measurement of bile acids and bilirubin, would further strengthen these findings

Mycologia 171:285289 Bowman BH, Taylor JW, White TJ (1992) Molecular evolution of the fungi: human pathogens

PubChem Reference: View compound profile on NIH PubChem Key Characteristics MOLECULAR PROFILE Formula: CHNO Weight: 751.87 g/mol CAS: 129954-34-3 Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro PHYSICAL PROPERTIES Form: White to off-white lyophilized powder Solubility: Readily soluble in water Storage: Keep refrigerated 3646 F (28 C)