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Mechanistically, [6]-shogaol reduces urate production through XOD inhibition, while SLN encapsulation provides multi-organ protective effects by mitigating drug degradation and improving biodistribution

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Because MS straddles the immune/degenerative divide, combining microbiome therapy with existing immunomodulatory drugs is an area of interest

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Most of the reported Lactobacillus species are considered beneficial microorganisms that improve gut functions by producing various secondary metabolites, including bacteriocin, lactic acid, and other organic acids (Ayivi et al., 2020