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doi: 10.3389/fimmu.2020.01007 Received 21 February 2020 Accepted 28 April 2020 Published 28 May 2020 Volume 11 - 2020 Edited by Laxmi Yeruva, University of Arkansas for Medical Sciences, United States Reviewed by Barbara Wrblewska, Institute of Animal Reproduction and Food Research (PAN), Poland

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Most recently, attention has shifted to proteosomal degradation of AR, with AR-targeting PROTACs being tested as a novel therapeutic option, and with drugs that possess a dual action as AR degrader and as AR antagonist under development [24, 25]