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Interestingly, glutathione also helps regenerate Vitamin C after it has been used

Copper deficiency impairs mitochondrial respiration, antioxidant defense, and vascular structural integrity, whereas copper overload triggers oxidative stress, inflammatory responses, and aberrant activation of cell death signaling

Some of the documented risks associated with long-term, high-dose IV glutathione use include: Kidney and Liver Dysfunction: The kidneys and liver are responsible for processing and filtering everything in your blood

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18 However, a recent study from Decante and colleagues 19 showed that both the transannular and the transpedicular approaches induced IDD as demonstrated by magnetic resonance imaging (MRI) and histological analysis in an ovine model