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Sep 2013;108(9):1508-15

Nat Commun 14(1):1829 Zhao Q et al (2019) Celastrol protects from cholestatic liver injury through modulation of SIRT1-FXR signaling

Over time, high-sugar intake leads to a chronic increase in the circulating number of pro-inflammatory cytokines and a general pro-inflammatory state

The promotion of SESN2 protein expression in CUMS mice significantly improves depressive symptoms while reducing levels of pro-inflammatory cytokines TNF- , IL-6, IL-1, and Iba-1 in the hippocampus, alleviating microglial activation and inflammation