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Description

Upregulation of NNMT drives the metabolic alteration and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents without reducing proliferation

The most affected phenotype identified was that of Igfbp4 ko mice who were growth retarded at birth and displayed poor postnatal growth (30)

10.1210/er.2008-0024 23 CovarrubiasA

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Why people use it: People have been drawn to TA-1 because of reports that it has helped with issues like long Covid and autoimmune disorders, which disproportionately affect women