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doi: 10.3389/fphar.2025.1709259 Received 19 September 2025 Revised 27 October 2025 Accepted 29 October 2025 Published 18 December 2025 Volume 16 - 2025 Edited by Vanessa Souza-Mello, Rio de Janeiro State University, Brazil Reviewed by Eduardo Duarte-Silva, University of Texas Health Science Center at Houston, United States Updates Copyright 2025 Cheng and Kim