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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

Data Availability Statement The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Are you targeting a specific enzymatic brake to restore NAD+ levels, or are you looking to activate a broad, systemic metabolic program that mimics exercise

This is often for people who need shots often or have less muscle