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Herner A, Sauliunaite D, Michalski CW, Erkan M, De Oliveira T, et al

doi: 10.1038/s41388-020-01622-3 71 DaiEHanLLiuJXieYKroemerGKlionskyDJet al

SSRIs, 5-HT4 partial agonists, 5-HT6 antagonists prevent both cognitive deficits and AD neuropathology and SSRIs increase A clearance in transgenic AD mouse models and humans [126,127,128,129,130,131,132,133,134]

doi: 10.1089/ars.2012.4581 11 RobbinsRJ

In another study, Tang and co-workers also achieved cervical cancer cell-selective mRNA delivery and CRISPR/Cas9 genome editing by designing phenylboronic acid (PBA) derived LNPs (PBA-BADP/p53 mRNA NPs) to prohibit cancer cell growth and show higher gene expression in HeLa cells over non-cancerous cells (Tang et al., 2019)