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4.3.5 Altered drug mechanism of action Repurposed drugs may exert their effect on the CNS tumor differently from their actions in the originally FDA-approved tumor type (108, 109)

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Acute tubular necrosis (ATN) scores were attenuated in the Luseo group compared to those in the vehicle group (Fig

The theory suggests these peptides may influence gene expression through epigenetic mechanisms, though the precise molecular interactions remain an area of ongoing investigation

Endogenous hydrogen sulfide overproduction in Down syndrome