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Utilizing retinal melanin as an endogenous detection material and intravenously injected gold nanorods as exogenous detection material, PT-OCT observes the photothermal effects on endogenous and exogenous substances in the retina, effectively adding a new source of contrast for structural OCT and marking a new era in ocular OCT examinations

Lipotoxicity in HepG2 cells triggered by free fatty acids

Available from: [6] Prescription Opioids DrugFacts National Institute on Drug Abuse (NIDA) [7] Understanding the Opioid Overdose Epidemic Centers for Disease Control and Prevention (CDC) [8] Schiller EY, Goyal A, Mechanic OJ

Its application resulted in increased cell proliferation, a significant rise in alkaline phosphatase (ALP) activity, positive Alizarin Red S staining, and the formation of mineralized nodules, as confirmed by EDX-SEM analysis

contributed equally

Furthermore, mitochondrial membrane potential (m) decline, increased mitochondrial outer membrane permeability and mitochondrial DNA (mtDNA) damage have been identified as key regulatory factors in ferroptosis (10,11)