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Brain Health Protecting the Brain: Glutathione is key for brain health

In particular, ADAR1mediated adenosinetoinosine RNA editing has been shown to modulate ferroptosis-regulated microRNAs such as let7d, which intersect with both TGF signaling and oxidative stress pathways

Notably, dietary vitamin E deficiency exacerbates these effects, whereas treatment with the ferroptosis inhibitor liproxstatin-1 significantly improves neuronal survival and behavioral outcomes (289)