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Hence, Chen et al

Extended IGF-1 Long-acting IGF-1 for muscle growth and recovery

Van Humbeeck C, Cornelissen T, Hofkens H, Mandemakers W, Gevaert K, De Strooper B, et al

used IL-1 receptor antagonist to antagonize IL-1, which reversed BBB damage and cognitive impairment after brain oxidative damage, confirming that IL-1 is an important factor mediating cognitive impairment in sepsis (Mina et al., 2014)

Another clinical study (NCT00913562) aimed to assess whether rosuvastatin could improve endothelial function in these patients, using flow-mediated vasodilatation of the brachial artery and flicker-induced vasodilatation of retinal vessels