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The specific order of these 15 amino acids is Gly-Glu-Pro-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Grgens C, Guddat S, Thomas A, Thevis M

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This complex will then phosphorylate IB, making it susceptible to degradation by proteasomes, resulting in nuclear translocation of NF-B, which in turn initiates the transcription of many genes that promote inflammation

For example, the optimal combination yielded a 131-fold increase in the expression of superfolder green fluorescent protein (sfGFP), while the highest yield was achieved after single-factor optimization (TIR) of the expression of DNA glycosylase Neil3, with a threefold increase, and combinatorial optimization produced only a twofold increase [22]