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I have also included oral folate supplements, probiotics and have expanded my diet (but still excluding caffeine, alcohol and sugar)

Taking too much can cause an upset stomach, nausea, cramps and diarrhea, vomiting, confusion, an irregular heartbeat, low blood pressure and more

NNMT had previously been identified as upregulated in obese adipose tissue, several solid tumours, and ageing tissue more broadly, where its activity correlates with depleted SAM and elevated 1-methylnicotinamide (MNA)