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This is the application area with the largest published literature base

Despite this warning research regarding AD has long been focused on the amyloid cascade hypothesis and strategies to prevent and/or remove plaques [2,8]

Spatiotemporally precise regulation: Develop tumor microenvironment-responsive prodrugs (e.g., DRP-104) to achieve localized induction of ammoniagenesis, thereby avoiding systemic toxicity

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic -cell turnover and function

Hypothermia can also be a manifestation of hyperammonemia [see Warnings and Precautions (5.11)]

Kennedy DO, Scholey AB, Wesnes KA