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Patients who experience a persistent sensation of tightness at the oral commissure and who present with distortion or retraction of the oral commissure, difficulty controlling a food bolus with chewing or frequent biting of the cheek during chewing, may be considered optimal candidates for botulinum toxin injection into this muscle

In fact, the debate still resembles the chicken and egg paradox, not being able to dissect what comes first

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Product analysis using GC and GCMS confirmed CH 3 OH as the main product, with no detectable signals in blank runs (no catalyst, dark, or N 2 flow), thus validating the photocatalytic origin