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LNPs delivering recombinant GCase (rGCase) were developed for Gaucher disease, bypassing the BBB via intranasal administration and restoring enzymatic activity in microglia, reducing substrate accumulation

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doi: 10.1016/j.ceb.2012.10.009 87 HebbarSKnustE

The absence of a statistically significant sequence effect was interpreted as evidence against a substantial carryover effect

treatment with two doses

N.T.Dintcheva, R.Arrigo, M.Baiamonte, P.Rizzarelli, G.Curcuruto Concentration-dependent anti-/pro-oxidant activity of natural phenolic compounds in bio-polyesters Polymer Degradation and Stability 142, 21-28 (2017) Abstract: In this work, the potential of several naturally occurring phenolic compounds, such as Ferulic Acid (FA), Vanillic Acid (VA), Vitamin E (VE) and Quercetin (Q), as stabilizers against the photo-oxidative degradation of Polylactic acid (PLA) has been assessed