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In a mouse kidney ischemia-reperfusion injury (IRI) model, Muller et al

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As hHGF is known to induce the branching morphogenesis 22,26,31 that builds epithelial architectures during embryogenesis, we finally examined whether the dimeric macrocycles could stimulate the formation of tubules in a population of RPTEC

Upon cellular uptake, MIRV is internalized via FR-mediated endocytosis, trafficked to lysosomes and reduced by glutathione to release DM4 and S-methyl-DM4

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