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However, a limitation of that study was that the number of subjects considered was very small [130]

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For any in-vivo animal research conducted in the United Kingdom, full compliance with the Animals (Scientific Procedures) Act 1986 (ASPA) is mandatory, requiring valid Home Office licences and institutional ethical approval

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They often involve certain devices and constituents like peel, LED therapy, microcurrents, microdermabrasion, Photorejuvenation, and more

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& Tarin, D

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aKG possesses a strong affinity for reactive oxygen species (ROS) released from the mitochondria, especially hydrogen peroxide, which it reacts with as a result of the conversion of succinate, carbon dioxide, and water, subsequently leading to its elimination [145]

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