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People on long-term metformin metformin reduces B12 absorption by up to 30% in some studies

Studies show that approximately 1% of a high-dose B12 supplement is absorbed through passive diffusion along the entire gastrointestinal tract, completely bypassing the need for Intrinsic Factor or perfect stomach acid levels

Why researchers call it an exercise mimetic The term means that the compound reproduced selected exercise-associated molecular signals in preclinical models