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Knockdown of endogenous GPX4 or blockade of GPX4 using a specific inhibitor enhanced the chemosensitivity of EBV-infected NPC cells

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Elevated ATF3 expression in aging osteocytes promotes iron uptake by upregulating TFR1 while inhibiting SLC7A11-mediated cystine uptake, leading to iron overload and lipid peroxidation, ultimately resulting in ferroptosis

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Signs and symptoms are more intense when the interval between the use of radiotherapy and the chemical trigger is shorter.28 There seems to be a radiation dose threshold that must be reached for recall dermatitis to develop

In glioblastoma, PHGDH binds to and stabilizes the transcription factor FOXM1, sustaining the expression of downstream targets (e.g., VEGF, CCND1, CHK2, and MMP-2 ) to drive glioma cell proliferation, invasion, and tumorigenicity [113] (Fig