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Funding This work was supported by grants from the National Natural Science Foundation of China (No.82072699)

Additionally, curcumin may influence ion channel activity, such as TRPM2, which is implicated in tumor progression and represents a promising therapeutic target in oncology ( Hormonal and metabolic effects Curcumin modulates several endocrine and metabolic pathways, notably those involved in insulin signaling and sex hormone regulation

Preventing with HPV Vaccine The HPV vaccine is specifically developed to protect the body against infections caused by certain high-risk strains of the Human Papillomavirus

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Additionally, proteins are the second abundant nutrient in mushroom which upon fermentation are denatured owing to enzymatic break down of proteins, and nucleic acids producing biogenic amines, which can survive after blanching (Jaboska-Ry et al., 2019a, 2019b, 2019c, 2019d)

The production of ROMs is increased significantly in PD due to mitochondrial energy crisis, aging, neuroinflammation, high levels of iron or Ca 2+ , and GSH depletion (Meiser et al., 2013)