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As shown in the simulation, whether using only the dynamical system without medication (4) or with medication (2), it is not possible to entirely cure the patient (since the M2 density is increasing)

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We also hope tirzepatide is accessible to patients who need it, and that providers will discuss other treatment options for the management of OSA along with lifestyle interventions when appropriate

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Their role is not to propose new OSC applications but to generate the mechanistic and safety evidence needed for responsible translation

Table 1 Genes commonly implicated in the onset of Parkinsons disease