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Chloroquine and Hydroxychloroquine These two antimalarial agents are commonly used in rheumatology practice for treating patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjgrens syndrome, based upon their immunomodulatory effects

Nucleic Acids Res 2002, 30, 18081816

-Tocopherol ( -TOC), a lipid-soluble molecule, is one of the eight variants of vitamin E and ubiquitous in plants and constitutes the predominant form in chloroplast photosynthetic tissues [3, 8]

In the absence of pathogen-specific trigger RNA, they sequester the RBS into a hairpin loop that blocks translation by the ribosome

PloS One (2016) 11:e0167218

Furthermore, it is important to note that high catalytic activity does not necessarily correlate with high therapeutic efficacy or greater potency