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Previously, glucocorticosteroids or NSAIDs were commonly used, which at best slowed joint damage and disability at the cost of significant toxicity

Journal of Psychoactive Drugs

Despite limited value of individual tau protein biomarkers in the early diagnosis of PD, the t-tau/t--Syn ratio, when combined with t--Syn levels in CSF, can greatly increase the accuracy of early PD diagnosis by allowing for better differentiation from AD or DLB (Frland et al., 2020)