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( A ) Under IL-13stimulated conditions, ALOX15 (15LO1) knockdown (KD) increases intracellular GSH and the GSH:GSSG ratio toward control conditions ( n = 6)

suum L3 with a constant resazurin concentration of 7.5 g/ml (Fig

This activity was confirmed via a luciferase reporter assay in a human 293T cell line

This forward-looking perspective underscores that energy metabolism functions not merely as a support system for neuronal activity but as a pivotal regulator in brain health and disease through mechanisms such as mitochondrial ATP synthesis, calcium buffering, and oxidative stress response (Nicholls and Budd, 2000)

Dagli et al., 1997

Yu Z.F., Bruce-Keller A.J., Goodman Y