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Mechanism: Innate Repair Receptor (IRR) Selective Agonist

MiR-15b-5p and PCSK9 inhibition reduces lipopolysaccharide-induced endothelial dysfunction by targeting SIRT4

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Furthermore, a key limitation of oral administration is the off-target effect, where most of the drugs may act on peripheral organs before they can reach the CNS

The update and integration of these lines of information may advance our understanding of the etiology, pathogenesis, phenomenology, and treatment of schizophrenia