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While glutathione is abundant in the liver, its production decreases with age, illness, and exposure to toxins

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Elevated TMAO levels have been linked to a number of diseases, including cardiovascular and neurological disorders, renal disease, metabolic syndrome, obesity, type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), cancer, and severe COVID-19

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Vogel K, Trotter J

FDA Review : If clinical trials are successful, the drug developer submits all data to the FDA

Cao and Li 2017)