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Adv Nutr 2014;5:5567

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Role and integration of EGFP-tagged MSCs in tissue regeneration The strategic injection of EGFP-tagged mesenchymal stem cells (MSCs) into the graft sites offered a unique perspective on their role in tissue regeneration

The major concerns: We dont have long-term safety data (20+ years) Youth uptake is a massive public health problem Many people end up dual-using (vaping AND smoking) Not FDA-approved for smoking cessation Variable quality and nicotine content between products Cost: $$ - Varies wildly depending on device and liquid Tier 3: Smoking Cessation Methods That Research Shows Probably Don't Work 11