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CBD rich Avidekel oil (extracted from Avidekel cannabis flower) induced lower sociability, reduced grooming time and shorter distance traveled, indicating an overall inhibitory effect [82]

1 Study design flowchart

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Due to the nature of our data (normal distribution, equal variance, small sample size, unpaired groups), Students t -test with FDR correction was used to assess differences in trichome count for trichome RAW fractions, whereas paired t -test was used to compute p -values concerning differences in trichome numbers between RAW and PURE trichome fractions (paired groups)

Moreover, recent frameworks extend these strategies to inflammatory and pulmonary diseases, where similar trigger-based principles guide the rational selection of linkers and cross-linking chemistries for in vitroin vivo correlation (Kalkal et al., 2025

Likewise, miR-19a-3p has been implicated in neuroinflammation through its interaction with tumor necrosis factor-alpha (TNF- ) (225, 232)