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2025;12(21):e2414559

Our study showed that the intrinsic circadian clock in the renal tubule exerted control over renal metabolism by regulating several key metabolic pathways, including carnitine shuttle, -oxidation of FAs, and nicotinamide (NAM) adenine dinucleotide (NAD + ) biosynthesis

However, when animals are fed diets high in protein, the protein content often exceeds their physiological needs, leading to resource wastage, increased production costs, and reduced economic efficiency (2)

In this state, the overactivation of N-methyl-D-aspartate receptor-type channels in L-glutamate (L-glu) channels mediates a large influx of Ca 2 , leading to cellular excitotoxicity and neuronal death

67,505 Ulefnersen (ION-363), an antisense therapy targeting the FUS gene, is currently in Phase III trials for FUS-ALS

hybridus , others classify it as a subspecies, and still others view it as an intermediate population involved in the domestication of A