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Given the critical role of mitochondrial ROS in psoriasis pathogenesis and the challenges of targeting them through conventional strategies, the proposed nanozyme-based approach provides an effective means to block NETosis at its origin and represents a promising therapeutic strategy for oxidative stress regulation

The dysregulated secretion of adipokines leads to insulin resistance and increased inflammation (406), while the intricate interplay between AT and the immune system becomes crucial in age-related metabolic decline, mirroring patterns observed in obesity (425)

J Biol Chem 274:1974519751 Nez B, Martnez de Mena R, Obregon MJ, Font-Llitjs M, Nunes V, Palacn M, Dumitrescu AM, Morte B, Bernal J (2014) Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation

- IGF-1 LR3 is a research peptide analog studied in models involving IGF-1 receptor signaling, cellular growth pathways, protein synthesis research, glucose-related signaling, tissue-response models, and anabolic pathway biology