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Mater Sci Eng C 92:644656

doi: 10.7554/eLife.91930 48 ParkerHAForresterLKaldorCDDickerhofNHamptonMBet al

Exposure to hydrogen peroxide induced severe fragmentation of DNA (71% of total DNA in tail) in control HEK293 cells

In contrast, phytochemical-derived chelators, nanotechnology-enabled delivery systems, enzyme-based detoxification, and microbiome-targeted interventions demonstrate enhanced specificity and reduced toxicity