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Under different pathophysiologic conditions, activated macrophages are capable of differentiating into phenotypically different states, including the classically activated (M1) and the alternatively activated (M2) macrophages

139 The measurement of short-chain fatty acids (SCFAs) in saliva, produced by causal bacteria, may be an indicator of the inflammation degree closely related to the onset and progression of periodontal disease

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In terms of neurodevelopment, excessive FA supplementation is associated with impaired neurocognitive development in children, which may lead to poor psychomotor development and an increased risk of autism [153]

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PubMed , Journal of Pharmacological Sciences , vol