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Among the 18 Arabidopsis SOT, there are two conserved cysteines (positions 199 and 270, AtSOT1 numbering) ( The SAL1 phosphatase, which is located both in chloroplasts and mitochondria, regulates PAP levels by dephosphorylating it to AMP

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doi: 10.1016/j.redox.2021.102041 19 BaH

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Food and Drug Administration-approved treatment for APAP overdose is N-acetylcysteine (NAC), a glutathione (GSH) precursor, administered alongside supportive therapy (European Association for the Study of the Liver