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KRAS mutation and metabolic alterations Cancer cells become dependent on activated oncogenes or their downstream metabolic processes for survival and proliferation [12]

Furthermore, it is documented that food in the gut can delay or prevent the uptake of small hydrophilic carbons such as HB (52, 53), probably explaining the lower circulating HB following food consumption (19)

INTRODUCTION Lower urinary tract symptoms (LUTS) refer to different symptoms divided into voiding, storage, or postvoiding including urinary hesitancy, straining, nocturia, increased urination frequency, and dysuria

doi: 10.1016/j.theriogenology.2025.117601 5 AleriJ

10.1097/mog.0000000000000589 19

Leaky gut syndrome allows for the release of pro-inflammatory microbial products such as lipopolysaccharide (LPS) into the bloodstream, wherein they immediately cross the gut-liver access and potentiate hepatic inflammation (Kessoku et al., 2021)