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Acute liver failure from paracetamol toxicity has a high mortality rate of 30% if there is no liver transplantation available[89,90]

However, the pronounced irregularity of the spherical vesicles and tubules induced by the SNX1-SNX2a heterodimer hindered the application of iterative helical real-space reconstruction, making it impractical to obtain high-resolution structural information for the complex

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These systems are summarized here and their implications are discussed

Quantitative real-time PCR (qRT-PCR) was performed using the BeyoFast SYBR Green One-Step qRT-PCR Kit (Beyotime, China) on an MX3000P Real-time PCR system (Stratagene, Germany)