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Ldecke et al., 1996)

Although the primary behavioral outcomes of addictive substances are realized through distinct effector mechanisms, such as neurotransmitter transporters, ion channels, and receptor proteins, the common feature of these drugs is concerned with increased dopamine neurotransmission within the mesocorticolimbic circuitry of the brain from the ventral tegmental area to the nucleus accumbens and prefrontal cortex [1]

it does not participate in the key biological processes but can sometimes interfere with them

Kawashima M, Ozawa Y, Shinmura K, Inaba T, Nakamura S, Kawakita T, et al

Research studies have used doses up to 3,000 mg/day (Salehpour 2019)

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