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doi: 10.1016/j.parkreldis.2019.03.009

PMC Copper Shuttle: Safely escorts bio-available copper into cells, a co-factor for collagen cross-linking enzymes like lysyl oxidase

The percentage of late apoptosis in THJ-16 cells increased from 5.49% for untreated cells to 63.43% for treated cells, while the corresponding percentage in CAL-62 cells increased from 16.72 to 69.88%

Typical dosage starts at 1,000 mcg weekly, but consult your physician for personalized guidance

A short trial of treatment with rhIGF-1 resulted in normalization of circulating IGF-I, suppression of GH hypersecretion and a markedly decreased insulin response to a meal tolerance test (91)

They are intended to support weight-loss efforts as part of a larger wellness plan that includes diet and exercise.