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To test whether PAEC-specific GATA6 deficiency is responsible for GATA6 downregulation in PASMC, we depleted GATA6 in HPAEC and treated non-diseased human PASMC with PAEC-conditioned media (PAEC-CM) (Fig

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Two regimensguadecitabine combined with pembrolizumab (NCT02901899), and atezolizumab combined with guadecitabine and the CDX-1401 vaccine (NCT03206047)have completed enrollment, with results pending release