glutathione synthesis mitochondria Controlling entry into mitochondria: potential roles for SLC25A39 in health and (treatment of) disease Energy status and redox potential

Energy status and redox potential are directly linked. We see this with glutathione where both steps in its synthesis require magnesiumATP, in order to make cysteine, glutamate, and glycine combine together Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis ScienceDirect Frontiers Glutathione and mitochondria regulation of glutathione synthesis Glutathione: an overview biosynthesis and modulation Controlling glutathione entry into mitochondria: Mitochondrial Glutathione: Regulation and Functions Gaetano Calabrese, Bruce Morgan, Jan Riemer, 2017 Pulling back the mitochondria's iron curtain npj Metabolic Health and Disease

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