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Its hepatoprotective effects are attributed to multiple mechanisms, including the modulation of lipid metabolism, antioxidant activity, anti-inflammatory properties, enhancement of insulin sensitivity, and alterations in gut microbiota composition

Recently, it has been shown that hepatic Fasn KO substantially ameliorated hepatic steatosis in multiple MASLD models, such as ob/ob and Mc4r -KO (50)

Suspected adverse reactions to metformin or B12 therapy should be reported via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)