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BPC-157 Mechanism of Action in Research Models BPC-157 appears to act through multiple biological pathways in preclinical studies

[6] Lei HL, Wei HJ, Chen PH, Hsi HC, Chien LC

Ethics approval The protocol is approved by the Portuguese National Ethics Committee (CEIC code 20160561) and the Institutional Review Board at Hospital da Luz, SA, Lisbon, Portugal (IRB protocol HL_001_2016)

(Basel) 14 (9), 942

Cysteine is the rate-limiting precursor for GSH synthesis, and SLC7A11, a multipass transmembrane protein, mediates cystine/glutamate antiporter activity in the system and regulates GSH synthesis to affect ferroptosis [5]