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A net increase of cytosolic calcium due to a diminished calcium storage is, therefore, obtained ( via the immediate formation of glutathione-DMF adducts ( Figure 1 The Role of Glutathione and DMF in Psoriasis Several studies have demonstrated that glutathione binding to DNA is able to regulate Nf-B proinflammatory activity

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These findings suggest that activation of glutamine metabolism plays a role in protecting AML cells after iCT treatment, and suggest the potential application value of controlling glutamine metabolism to continuously eliminate AML cells

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Molecules 27(2)