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Results of cellular thermal shift assay and molecular docking indicate that GPX4 is a potential direct target of carnosine, and carnosine shows promise as a potential inhibitor of ferroptosis for the treatment of renal I/R injury and other conditions associated with ferroptosis

doi: 10.1186/1471-2458-11-402 34 NezMNunezEDel ValJLJ

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Subjects with a known history of diabetes, coronary artery disease, neurological disorders, pelvic trauma, major psychiatric disorders, thyroid disease, end-stage renal disease, or vitamin deficiencies were excluded from the study